💓health points

A weighted scientific score that ranks compounds by the strength of their lifespan extension evidence across animal models — helping you identify the most promising interventions for life extension.

🧬 What Are Health Points?

Health Points are a score that reflects the scientific potential of each compound based on lifespan extension data from animal experiments.

On the Pump Science platform, Health Points are the primary metric used to rank and sort tokens in the main dashboard table.

🔢 Calculation Overview

The score is calculated as a weighted average of the observed effects in different animal models (e.g. worms, flies), adjusted for both:

• Similarity to humans

• Fidelity to lifespan outcomes

• Sample size (number of animals tested)

🧮 Formula

Health Points = Σ(Wj × Eij) / Σ(Wj)

Wj = Nj × Sj × Fj

• Nj = Number of animals used for organism j

• Sj = Proteomic similarity to humans

• Fj = Fidelity of experimental endpoint to true lifespan

• Eij = Lifespan extension (%) for organism j

🧪 Organism Weight Configuration

Organism	Proteomic Similarity (Sj)	Fidelity (Fj)	Weight Formula
Worms	0.4	1.0	W = N × 0.4
Flies	0.6	1.0	W = N × 0.6

Note: Mice and humans are not yet included in this score.

📊 Example Calculation

Scenario:

• 100 worms show a +10.5% lifespan extension

• 50 flies show a +15.2% lifespan extension

Worms: 100 × 0.4 × 1.0 = 40 → 40 × 10.5 = 420 Flies: 50 × 0.6 × 1.0 = 30 → 30 × 15.2 = 456

Total Health Points = (420 + 456) / (40 + 30) = 876 / 70 = +12.5