# health points

### 🧬 What Are Health Points?

**Health Points** are a  score that reflects the scientific potential of each compound based on lifespan extension data from animal experiments.

On the Pump Science platform, **Health Points are the primary metric used to rank and sort tokens** in the main dashboard table.

### 🔢 Calculation Overview

The score is calculated as a **weighted average** of the observed effects in different animal models (e.g. worms, flies), adjusted for both:

* **Similarity to humans**
* **Fidelity to lifespan outcomes**
* **Sample size (number of animals tested)**

### 🧮 Formula

Health Points = Σ(Wj × Eij) / Σ(Wj)

Wj = Nj × Sj × Fj

* Nj = Number of animals used for organism j
* Sj = Proteomic similarity to humans
* Fj = Fidelity of experimental endpoint to true lifespan
* Eij = Lifespan extension (%) for organism j

### 🧪 Organism Weight Configuration

| Organism | Proteomic Similarity (Sj) | Fidelity (Fj) | Weight Formula |
| -------- | ------------------------- | ------------- | -------------- |
| Worms    | 0.4                       | 1.0           | W = N × 0.4    |
| Flies    | 0.6                       | 1.0           | W = N × 0.6    |

*Note: Mice and humans are not yet included in this score.*

### 📊 Example Calculation

**Scenario:**

* 100 worms show a +10.5% lifespan extension
* 50 flies show a +15.2% lifespan extension

Worms: 100 × 0.4 × 1.0 = 40 → 40 × 10.5 = 420\
Flies: 50 × 0.6 × 1.0 = 30 → 30 × 15.2 = 456

Total Health Points = (420 + 456) / (40 + 30) = 876 / 70 = **+12.5**


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