health points
A weighted scientific score that ranks compounds by the strength of their lifespan extension evidence across animal models โ helping you identify the most promising interventions for life extension.
๐งฌ What Are Health Points?
Health Points are a score that reflects the scientific potential of each compound based on lifespan extension data from animal experiments.
On the Pump Science platform, Health Points are the primary metric used to rank and sort tokens in the main dashboard table.
๐ข Calculation Overview
The score is calculated as a weighted average of the observed effects in different animal models (e.g. worms, flies), adjusted for both:
Similarity to humans
Fidelity to lifespan outcomes
Sample size (number of animals tested)
๐งฎ Formula
Health Points = ฮฃ(Wj ร Eij) / ฮฃ(Wj)
Wj = Nj ร Sj ร Fj
Nj = Number of animals used for organism j
Sj = Proteomic similarity to humans
Fj = Fidelity of experimental endpoint to true lifespan
Eij = Lifespan extension (%) for organism j
๐งช Organism Weight Configuration
Worms
0.4
1.0
W = N ร 0.4
Flies
0.6
1.0
W = N ร 0.6
Note: Mice and humans are not yet included in this score.
๐ Example Calculation
Scenario:
100 worms show a +10.5% lifespan extension
50 flies show a +15.2% lifespan extension
Worms: 100 ร 0.4 ร 1.0 = 40 โ 40 ร 10.5 = 420 Flies: 50 ร 0.6 ร 1.0 = 30 โ 30 ร 15.2 = 456
Total Health Points = (420 + 456) / (40 + 30) = 876 / 70 = +12.5
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